top of page
SPARC News
Open Source Drug Discovery 2.0: A hybrid IP and incentive framework for democratising translational AI drug research
Jake Y. Chen, PhD Systems Pharmacology Research Center (SPARC) School of Medicine of the University of Alabama at Birmingham...
2 hours ago9 min read
Â
Â
Â
Join the Open IP‑Gating Pilot: Validating the First Open Alzheimer’s Drug Candidate
Introduction The Open Source Drug Discovery 2.0 (OSDD‑2) framework invites researchers, clinicians and innovators to participate in the...
1 day ago3 min read
Â
Â
Â
Blocking Memory Loss: Delta Opioid Receptor Antagonists Prevent Alzheimer’s Pathology
New Class of Compounds Shows Neuroprotection, Plaque Reduction, and Strong Drug-Like Properties Birmingham, AL – Sep 25, 2025 –  ...
Sep 252 min read
Â
Â
Â
The Importance of Systems in Modern Drug Research
Modern drug research is a complex and multifaceted process that requires precision, innovation, and collaboration. The integration of...
Sep 153 min read
Â
Â
Â
Flu Fighters: High-Throughput Screening Uncovers New Influenza A Inhibitors
200,000 Compounds Screened, 3 Novel Drug Scaffolds Identified, and Deep Learning on the Horizon Birmingham, AL  – As seasonal and...
Jun 272 min read
Â
Â
Â
Gene Expression, Reimagined: New AI Tool Reveals Temporal Shifts in Cancer Drug Response
Temporal GeneTerrain Maps Dynamic Drug-Induced Pathways in Prostate Cancer Cells Birmingham, AL  – A team of biomedical informatics...
Jun 172 min read
Â
Â
Â
LlamaAffinity: AI-Powered Leap in Predicting Antibody–Antigen Binding
A Llama 3-Based Deep Learning Model Outperforms State-of-the-Art Antibody Binding Predictors Birmingham, AL  – In a major leap forward...
May 282 min read
Â
Â
Â
New Publication in the Journal of Medicinal Chemistry
We’re thrilled to share that our latest research on LRRK2 molecular dynamics (MD) simulations , led by Dr. Bhakat , has just been...
May 161 min read
Â
Â
Â
bottom of page